Dapsone For Morgellons?

What about Dapsone for Morgellons? Several reports are trickling in about the potential for a repurposed “leprosy” drug to assist in eradicating spirochetal persister cells. Recently, Dr. Richard Horowitz published research which demonstrates efficacy of Dapsone in combination with other antibiotics. First, let’s review the science.

Dapsone For Lyme Disease

“Three patients with multi-year histories of relapsing and remitting Lyme disease and associated co-infections despite extended antibiotic therapy were each given double-dose dapsone combination therapy (DDD CT) for a total of 7-8 weeks. At the completion of therapy, all three patients’ major Lyme symptoms remained in remission for a period of 25-30 months. A retrospective chart review of 37 additional patients undergoing DDD CT therapy (40 patients in total) was also performed, which demonstrated tick-borne symptom improvements in 98% of patients, with 45% remaining in remission for 1 year or longer. In conclusion, double-dose dapsone therapy could represent a novel and effective anti-infective strategy in chronic Lyme disease/ post-treatment Lyme disease syndrome (PTLDS), especially in those individuals who have failed regular dose dapsone combination therapy (DDS CT) or standard antibiotic protocols. A randomized, blinded, placebo-controlled trial is warranted to evaluate the efficacy of DDD CT in those individuals with chronic Lyme disease/PTLDS.”

Efficacy of Double-Dose Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post-Treatment Lyme Disease Syndrome (PTLDS) and Associated Co-infections: A Report of Three Cases and Retrospective Chart Review – PubMed (nih.gov)

What Do Doctors Think About Dapsone?

Next, we wanted to look at what doctors who have treated Lyme think about Dapsone. Dr. Marty Ross was one of the first professionals to report on this potentially exciting breakthrough therapy.

The American Integrative Pharmacy produced an informative article about Dapsone in the treatment of Chronic Lyme Disease as well.

Dapsone or diaminodiphenyl sulfone (DDS) is a commonly used drug to treat skin conditions such as dermatitis herpetiformis, leprosy and acne. A know persister bacteria called mycobacterium leprae requires long-term treatment with intra cellular drugs, which include Dapsone. Other persister bacteria that have been identified in recent years include Borrelia burgdorferi, which is considered to be an agent of Lyme disease.

Using Dapsone in the Treatment of Chronic Lyme Disease | Long Beach (americanintegrative.com)

So What About Dapsone For Morgellons?

Both the Lyme Disease Association and LymeDisease.Org authored favorable articles about Dapsone for Lyme, but as always – we recommend against seeking this therapy on your own. Please consult a board certified medical doctor to see if this medicine is right for your particular case, or if it might be a risk you should rather avoid.

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