Research Library • Peer-Reviewed Papers • Clinical Context
Morgellons Disease Research Library
A focused research page for published papers, case reports, filament studies, spirochetal association papers, clinical evaluations, and balanced discussion of differential diagnosis.
Educational information only. These papers help organize the discussion, but they do not replace evaluation by a licensed clinician.
Research Library
Morgellons Disease Research Papers
The following sources directly address Morgellons disease, cutaneous filaments, Borrelia or spirochetal associations, clinical evaluation, differential diagnosis, or related dermatological questions. Most are peer-reviewed; one recent entry is a preprint and is clearly marked as not yet peer-reviewed.
F1000Research
Association of Spirochetal Infection with Morgellons Disease
A frequently cited paper examining the association between Morgellons disease and spirochetal infection.
Clinical, Cosmetic and Investigational Dermatology
Characterization and Evolution of Dermal Filaments from Patients with Morgellons Disease
Examines dermal filaments and their composition in Morgellons disease specimens.
Clinical, Cosmetic and Investigational Dermatology
Classification and Staging of Morgellons Disease: Lessons from Syphilis
Discusses Morgellons disease classification and staging using syphilis as a clinical comparison point.
Dermatology Reports
Clinical Evaluation of Morgellons Disease in a Cohort of North American Patients
A clinical evaluation of a North American Morgellons disease patient cohort.
BMC Dermatology
Exploring the Association Between Morgellons Disease and Lyme Disease
Reports identification of Borrelia burgdorferi in Morgellons disease patients.
Clinical, Cosmetic and Investigational Dermatology
Filament Formation Associated with Spirochetal Infection
A comparative approach to Morgellons disease and filament formation associated with spirochetal infection.
Clinical, Cosmetic and Investigational Dermatology
History of Morgellons Disease: From Delusion to Definition
A historical and scientific review of how Morgellons disease has been framed and debated.
International Journal of General Medicine
Morgellons Disease: A Filamentous Borrelial Dermatitis
A key paper describing Morgellons disease as a filamentous borrelial dermatitis.
Clinical, Cosmetic and Investigational Dermatology
Dermatological and Genital Manifestations of Lyme Disease Including Morgellons Disease
Discusses Lyme-related dermatological manifestations, including Morgellons disease presentations.
Psychology Research and Behavior Management
Reframing Delusional Infestation: Perspectives on Unresolved Puzzles
A secondary review (Lai et al., 2018) arguing that Morgellons disease is not simply a subtype of delusional infestation, and proposing a multifactorial approach to diagnosis.
Preprint • bioRxiv (2026)
Metagenomics Reveals a Phylogenetically Informed Microbial Signature Associated with Morgellons Disease
Deep metagenomic sequencing comparing lesions to unaffected skin across a five-person family cohort (Lambert & Kindschuh). It reports a microbial signature associated with lesions and sequences poorly represented in existing databases. Preprint — not yet peer-reviewed, and based on a single small family cohort.
