In April 2026, a preprint appeared on bioRxiv with a title that got a lot of people’s attention: Metagenomics reveals a phylogenetically informed microbial signature associated with Morgellons disease. The authors, Andrea Nicole Lambert and William Kindschuh, ran deep metagenomic sequencing on lesion samples and unaffected skin from five members of a single family, all reporting Morgellons symptoms. It is, as far as I can tell, the first time anyone has pointed this particular tool — deep shotgun sequencing of everything genetic in a sample — at Morgellons lesions. In effect, it’s the first Morgellons metagenomic study of its kind.
